Playing around with Instagram today I found out about two desktop applications for the Mac that allow you to interact with your Instagram feed from your Mac desktop.
Neither allow you to post from the Mac (which is a pity) but both do allow you to “like” and “comment” on the images from your feed.
Uploading images is forbidden by Instagram which allows only uploads from mobile devices.
InstaDesk lets you not only browse your or your friends Instagram pictures, but easily explore the social graph and find new people to follow.
Instead, with InstaDesk you can browse beautiful pictures, newest uploads of your friends, or interesting people to follow. Furthermore, you can comment on pictures, like them, download them, or watch them in slideshows.
Carousel is a simple, beautiful way to explore Instagram on your Mac in a minimal footprint. View your feed, popular photos, your photos, comment, like, save photos and much, much more. We’ve also implemented a full set of keyboard commands to make operation flawless and four wonderful themes to personalize Carousel to your liking.
Of course there are a few web based services out there that allow you to view your Instagram feed in a browser. However the couple I have tried are either not very reliable or are limited in how you can share feeds with non-Instagram users (not that you can do that with a desktop app).
Though Twitter is available in the browser, lots of people use Desktop Apps to access Twitter, these apps for Instagram may work for you allowing you to access your Instagram feed from your Mac rather than your iPhone.